The Pellicon® Capsule is the first of its kind -- a true single-use TFF device that comes ready to process in minutes. Self-contained, it employs an easy-to-use, holderless format and is supplied gamma sterilized with preservative-free reverse osmosis water.
This new addition to the Pellicon® family shares the same unbeatable performance of Pellicon® cassettes and are linearly scalable, making it easy to transition between both formats.
Pellicon® Capsules are ideal for the filtration of solutions that require single-use capabilities, including
- Rapid batch turnaround for higher plant productivity
- Lower risks of product cross-contamination
- Self-contained device for increased operator safety
- Process flexibility for multi-product manufacturing facilities
- Optimum use of time and resources from minimal device preparation
Membrane
Pellicon® Capsules with Ultracel® membrane are designed for excellent product retention, recovery, and high yields. Ultracel® void-free composite membranes combine ultra-low protein binding, low fouling, and organic solvent resistance with superb mechanical strength.
Benefits
- Plug ’n play, holderless design -- easy to install, safe to remove
- Gamma sterilized and preservative-free -- ready to process in minutes
- True single-use, self-contained capsule -- fast, safe, and flexible batch turnaround
- Proven Ultracel® membrane and C screen -- high recovery, superior mass transfer, solvent resistance
- Pellicon® TFF proven performance -- true linear scalability within Pellicon® TFF families
Applications
- Antibody drug conjugates
- Monoclonal and bispecific antibodies
- mRNA and plasmids
- Viral vectors and viral vaccines
- Recombinant and non-recombinant proteins